Welcome Guest
Sign In
Register
Products
Popular Categories
Antibody Search
ELISA Kit Search
Biomolecules
Flow Cytometers
Thermal Cyclers
Microscopes
Transfection Reagents
Featured Products
New Products
Articles
Resources
eBooks
Bench Tips
Tech Insights
Editorial Articles
News
Product Reviews
Future Lab
Multimedia
Biocompare Webinars
Immunotherapy
Reproducibility
Transformative Technologies
Podcasts
Tech Talks
Bench Tip Videos
All Videos and Webinars
Life Science Webinars
Write a Review
Antibodies
Kits/Reagents
Equipment
Services
Resources
Promotions
Events
AACR SPOTLIGHT
Register
Sign In
Biocompare
Products
Protein Biochemistry
Chemicals and Reagents
Ko 143
Ko 143 from Cayman Chemical
Be the first to write a review!
Citations:
(2)
Supplier Page
Supplier Page from
Cayman Chemical for
Ko 143
Request Info
Description
A potent and selective inhibitor of BCRP, preventing the export of mitoxantrone and topotecan in breast cancer cell lines (EC50s = 23 and 26 nM, respectively); effective in vivo in mice
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Ko 143
Company
Cayman Chemical
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
15215
Format
A crystalline solid
Research Area
Cancer, Multidrug Resistance
Molecular Weight
469.6
Quantity
50 mg
Purity
≥98%
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
The inhibition of ABCB1/MDR1 or ABCG2/BCRP enables doxorubicin to eliminate liver cancer stem cells
Scientific Reports
December 1, 2021
Wang Yin et al.
were treated with DOX (Sigma, #44583) plus verapamil (
Sigma
, #SML0572) or
ko143
(
Cayman Chemical
, #
15215
) or siRNA against MDR1 or ABCG2 mRNA. Supplementary Table ST2 summarizes the sequences of siRNAs used
(2)
Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes
Nature medicine
June 1, 2020
Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT,
et al
.
rhodamine 123 (
ThermoFisher
,
R302
) and Hoechst dye, 5μM reversine 121, or 5 μM KO143 (
Cayman Chemical
15215
) for one hour at 37°C. 3D Cultures 1 × 106 BECs/ml, and 2 × 105
Astrocytes
/ml and 2 × 105
pericytes
/ml
<<
<
>
>>
Reviews
Be the First to Write a Review!
Ko 143 from Cayman Chemical
Supplier Page
View Company Product Page
Pricing Info
Product Specs
Company Info
Citations
Reviews
Back To Top